Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on X , Facebook , Instagram , YouTube , LinkedIn and Tik Tok .
Job Description
The Scientist II, Fermentation will be an instrumental team member of the Neurotoxin & Biologics Process Sciences Department, based in Irvine, CA. The primary role of this position is to plan, design studies, execute experiments and develop processes to support the fermentation of natural and recombinant proteins from bacterial cell cultures. The scientist will support studies at small and intermediate scale during various stages of development including cell line development, upstream process development and process optimization. The fermentation scientist will independently operate small- and intermediate-scale upstream equipment (Ambr® 250, Biostat® B-DCU, single-use fermentors, steam-in-place fermentors, microfluidizers, CIP skid etc.).
The scientist in this position is expected to demonstrate a significant level of hands-on experience and in-depth knowledge in upstream processes. This individual will design and execute the studies by applying quality by design (QbD), scientific and/or engineering principles & practices, scale-up & scale-down model qualifications, and daily operations of upstream activities. Significant experience authoring standard operating procedures (SOPs), technical reports to support phase-appropriate process development and technology transfer is preferred. Additional responsibilities include data analysis, troubleshooting process and equipment, participation in project teams, lab inventory and organization, maintaining detailed records of batches and experiments. Experience performing molecular biology or microbiology work such as cloning, polymerase chain reaction (PCR), and bacterial colony selection is prefered, but not required.
An ideal candidate would have the ability to work as an integral part of an upstream team. This individual will support drug discovery and downstream teams, as well as demonstrate a high degree of flexibility, creativity, and initiative for the various duties and aspects of position.
Furthermore, the position requires the individual to work with regulated Select Agents and Toxins access (i.e. Biosafety level 2 and biosafety level 3 laboratories). Access to and use of select agents is regulated by federal policies. Therefore, the candidate must conduct all work activities in compliance with AbbVie internal and applicable regulatory requirements including health screening and background checks. AbbVie internal requirements include compliance with ethics, environmental health and safety, financial, human resources, and general business policies, requirements and objectives.
Essential Skills / Responsibilities:
Qualifications
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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